The Ramses station in central Cairo was set ablaze after a train collided with the platform and its fuel tank exploded, state-run news site Al-Ahram reported, citing security sources.
The deadly incident prompted Egypt’s Transportation Minister Hisham Arafat to resign, according to Al-Ahram.
Egypt’s Health Minister, Hala Zayed, told reporters in a televised press conference that many of the injured are in a critical condition, with second- and third-degree burns. Thirty ambulances were on site, but people in the area volunteered to take some of the injured to the hospital in their own cars.
Egypt’s Prosecutor General, Nabil Sadek, has ordered an investigation, according to Al-Ahram. President Abdel Fattah el-Sisi has also vowed to bring those responsible for the accident to justice.
“People were screaming, and there were calls on the station’s microphone for people to evacuate,” eyewitness Ahmed Ibrahim told CNN.
“I saw this (injured) girl and I felt she is like my daughter. I carried her out in a blanket,” Ibrahim said.
Another eyewitness, Sami Rafaat, told CNN: “I saw the train speeding as if it were not entering the station but was in a race. Then there were bodies on the platform and on the tracks. They were completely burnt.”
Two eyewitnesses said they saw the driver jump out of the train as it approached the station.
Images posted on social media showed charred bodies at the busy station in the heart of the capital. Other online photos revealed a blackened platform and smoke billowing from the station.
CCTV footage broadcast on local media showed people, some on fire, running away from the platform.
More than an hour after the collision, body parts were still scattered around a restroom near the site of the collision, and marks left by charred bodies stained the platform.
Egypt has a history of deadly train disasters, with the most lethal one occurring in 2002, when a fire on a passenger train killed more than 320 people.
Government records show 14,349 train accidents between 2005 and 2017. The worst year was 2017, which saw 1,793 incidents, according to the Central Agency for Public Mobilization and Statistics.
Journalist Magdy Samaan reported from Cairo, while CNN’s Sarah El Sirgany reported from Abu Dhabi, United Arab Emirates, and Sheena McKenzie wrote in London. CNN’s Tamara Qiblawi, Hamdi Alkhshali and Gianluca Mezzofiore contributed to this report.